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Fig. 2 | BMC Cancer

Fig. 2

From: DAB2IP down-regulates HSP90AA1 to inhibit the malignant biological behaviors of colorectal cancer

Fig. 2

DAB2IP regulates the malignant behavior of CRC cells through HSP90AA1. a CCK8 assay demonstrated that DAB2IP regulated the proliferation of CRC cells by HSP90AA1. *P < 0.05, ** P < 0.01, ***P < 0.001, ****P < 0.0001. The data were expressed as mean ± SD, n = 3. b c Apoptosis of CRC cells was regulated by DAB2IP/ HSP90AA1 signal pathway, quantification at the bottom. Apoptosis was analyzed by measuring Annexin V-PE positive cells by flow cytometry. *P < 0.05, ** P < 0.01, ***P < 0.001, ****P < 0.0001. The data were expressed as mean ± SD, n = 3. d e Transwell assay and Wound scratch assay demonstrated that DAB2IP regulated the migration of CRC cells by regulating HSP90AA1 expression, quantification at the bottom. *P < 0.05, ** P < 0.01, ***P < 0.001, ****P < 0.0001. The data were expressed as mean ± SD, n = 3

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