Table 6 Univariate and multivariate analyses of disease-free survival

Sex

  Male

1[reference]

  Female

0.878 (0.509-1.517)

0.642

Age (years)

1.017 (0.991-1.044)

0.211

-

-

BMI

0.978 (0.895-1.068)

0.620

-

-

CEA (ng/ml)

1.008 (1.000-1.017)

0.051

-

-

CA19-9 (U/ml)

1.002 (1.001-1.004)

<0.001

1.002 (1.001-1.003)

0.005

Tumor location

  Middle and Upper third

1[reference]

  Lower third

0.923 (0.553-1.542)

0.759

  Entire stomach

3.050 (0.406-22.919)

0.279

Histological type

  Well to moderately differentialed

1[reference]

1[reference]

  Poor differentialed

1.494 (0.703-3.178)

0.297

1.345 (0.619-2.922)

0.453

  Signet ring cell

1.020 (0.314-3.312)

0.974

0.556 (0.168-1.835)

0.335

  Mucinous

2.974 (1.410-6.272)

0.004

2.508 (1.167-5.389)

0.019

  Tumor size (mm)

1.008 (0.997-1.019)

0.163

-

-

pTNM stage

  I-II

1[reference]

1[reference]

  III

5.453 (2.973-10.001)

<0.001

4.151 (2.011-8.570)

<0.001

AADAC

  Low expression

1[reference]

1[reference]

  High expression

0.469 (0.281-0.783)

0.004

0.432 (0.255-0.731)

0.002

  mLNR

30.128 (11.074-81.966)

<0.001

3.113 (0.680-14.238)

0.143

Vascular infiltration

  No

1[reference]

  Yes

1.598 (0.990-2.581)

0.055

Nerve infiltration

  No

1[reference]

  Yes

1.286 (0.801-2.065)

0.299

Postoperative chemotherapy

  Yes

1[reference]

0.990

  No

0.997 (0.618-1.609)