Fig. 3
From: Deletion of TRIB3 disrupts the tumor progression induced by integrin αvβ3 in lung cancer
Integrin αvβ3 induced tumor progression was TRIB3 dependent. A, the expression of TRIB3 in para-carcinoma tissues (n = 59) and tumor tissues (n = 515) from NSCLC patients. B, the overall survival of NSCLC patients divided into high TRIB expression group (n = 127) and low TRIB expression (n = 375). C, western blotting of TRIB3 in vector control, TRIB3 silenced #1 and TRIB3 silenced A549/PC-9. D, relative cell proliferation of vector control, TRIB3 silenced #1 and TRIB3 silenced A549/PC-9 (integrin αvβ3 positive). E, relative cell proliferation of vector control, TRIB3 silenced #1 and TRIB3 silenced A549/PC-9 (integrin αvβ3 negative). F, the colony formation rates of vector control, TRIB3 silenced #1 and TRIB3 silenced A549/PC-9 (integrin αvβ3 positive). G, relative migrating cell numbers of vector control, TRIB3 silenced #1 and TRIB3 silenced A549/PC-9 (integrin αvβ3 positive). * means p < 0.05, ** means p < 0.01