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Table 2 Univariate and multivariate Cox regression analysis between the clinical features and OS in the TCGA-HCC cohort

From: Identification of immune infiltration-related genes as prognostic indicators for hepatocellular carcinoma

Characteristics

Total(N)

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

T stage

370

    

T1&T2

277

Reference

   

T4&T3

93

2.598 (1.826–3.697)

< 0.001

2.021 (1.389–2.941)

< 0.001

Gender

373

    

Female

121

Reference

   

Male

252

0.793 (0.557–1.130)

0.200

  

Age

373

    

<=60

177

Reference

   

> 60

196

1.205 (0.850–1.708)

0.295

  

Residual tumor

344

    

R0

326

Reference

   

R1&R2

18

1.604 (0.812–3.169)

0.174

  

Histologic grade

368

    

G1

55

Reference

   

G2

178

1.162 (0.686–1.968)

0.577

  

G3&G4

135

1.222 (0.710–2.103)

0.469

  

AFP (ng/ml)

279

    

<=400

215

Reference

   

> 400

64

1.075 (0.658–1.759)

0.772

  

Vascular invasion

317

    

No

208

Reference

   

Yes

109

1.344 (0.887–2.035)

0.163

  

Tumor status

354

    

Tumor free

202

Reference

   

With tumor

152

2.317 (1.590–3.376)

< 0.001

1.832 (1.242–2.701)

0.002

riskgroup

373

    

Low

186

Reference

   

High

187

2.924 (2.014–4.244)

< 0.001

2.672 (1.800–3.968)

< 0.001

  1. Annotation: HR Hazard Ratio, 95%CI 95% confidence interval
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