Fig. 6
Disulfiram/copper complex inhibits LGR5-positive cervical cancer cells in vivo. a Suppression of tumor growth after DSF/Cu and DDP treatment in female BALB/c-nude mice. b-c The volume of xenograft tumors formed by LGR5LGR5+ and AcGFPLGR5- cervical cancer cells with different drug delivery was monitored over time. d-e At the end of the experiment, the tumor weights were measured. f-g Kaplan-Meier plots showing the tumor-free survival after injection. Data represent mean ± S.D. of tumor volumes or weights of eight mice in each group. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001