Fig. 7
From: BARD1 mystery: tumor suppressors are cancer susceptibility genes
BARD1/BLM co-expression correlated with worse patient outcomes and aggressive breast cancer phenotype: A, B & C Represent the high expression of BARD1 gene is significantly associated with worse OS (P = 0.00038), RFS (P = 1.4^-16), and DMFS (P = 1.8^-08), by KM-Plot. D BARD1-BLM gene signuture expression level according to breast cancer molecular subtypes, basal (304), HER2 + (240), Luminal A, LA (465), Luminal B, LB (471), Normal like, NL (304), and Unclassified, UC (97). E BARD1-BLM gene signuture expression level according to ER status, ER- (395) and ER+ (1225). F BARD1-BLM gene signuture expression level in correlation with histological grades, G1 (239), G2 (677), and G3 (495), by GOBO. Source: The Kaplan-Meier Plotter, (https://kmplot.com/analysis/) [71]. Gene expression-based Outcome for Breast cancer (GOBO) online database (http://co.bmc.lu.se/gobo/) [60]