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Table 2 Gene association analysis. Top three genes associated with KC and exclusive development of BCCs or SCCs

From: Associations of keratinocyte cancers with snp variants in the sonic hedgehog pathway

KC vs Controls (total n = 795)
Chromosome Gene   No of SNPs analysed in gene Z score P value
 9 PRKACG protein kinase cAMP-activated catalytic subunit gamma 4 2.2271 0.01297
 3 GSK3B glycogen synthase kinase 3 beta 29 1.5958 0.05526
 7 SHH sonic hedgehog signaling molecule 5 1.3246 0.09266
BCCs exclusively vs Controls (total n = 670)
Chromosome Gene   No of SNPs analysed in gene Z score P value
 7 SHH sonic hedgehog signaling molecule 5 2.5477 0.00542
 3 GSK3B glycogen synthase kinase 3 beta 29 1.8958 0.02899
 9 PRKACG protein kinase cAMP-activated catalytic subunit gamma 4 1.7328 0.01214
SCCs exclusively vs Controls (total n = 539)
Chromosome Gene   No of SNPs analysed in gene Z score P value
 15 KIF7 kinesin family member 7 4 2.3964 0.00828
 18 BCL2 BCL2 apoptosis regulator 73 2.2388 0.01258
 5 CSNK1G3 casein kinase 1 gamma 3 8 2.0339 0.02098