Fig. 1From: Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem-ion): study protocol for a randomized phase II pilot trialTarget volume delineation and treatment planning: A The gross target volume (GTV) is depicted in green and encompassed by the clinical target volume in orange (CTV) with a margin of 3-4 cm in the longitudinal and 1.5-2 cm in the lateral direction. B The metallic wire marking the planned surgical incision is delineated and encompassed by a 2 cm margin for skin sparing if possible. C Dose distribution using opposing beams, the area of beam entrance was chosen outside of the region destined for surgical incision, treatment was performed with carbon ionsBack to article page