Table 3 Multivariate Cox regression analyses for overall survival and disease-free survival using significant univariate variables in the TTBD series (final multivariate model)

FBL

 Intermediate

0.0042*

1.00

0.0149*

 Low

[1.41–3.92]

2.02

[1.21–3.39]

 High

[0.72–2.24]

1.56

[0.94–2.56]

NOP58

 Low

removed

removed

 High

Tumor size

  < 30 mm

 < 0.0001***

1.00

0.0002**

  ≥ 30 mm

[1.77–4.33]

2.14

[1.44–3.18]

Lymph node invasion status

 N = 0

0.0443*

1.00

0.0174*

 N ≥ 1

[1.01–2.55]

1.64

[1.09–2.48]

Breast cancer subtypes

 ER + PR ± HER2-

0.0463*

N/A

N/A

 ER ± PR ± HER2 + 

[0.63–1.79]

 ER- PR- HER2-

[1.12–3.35]