Table 2 Multivariate Cox regression analyses for overall survival and disease-free survival using significant univariate variables in the TTBD series (Step with NOP58 that was removed from the model)

FBL

 Intermediate

0.0230*

1.00

0.0149*

 Low

[1.24–3.74]

2.02

[1.21–3.39]

 High

[0.74–2.34]

1.56

[0.94–2.56]

NOP58

 Low

0.4034

1.00

0.3036

 High

[0.73–2.22]

1.32

[0.78–2.24]

Tumor size

  < 30 mm

 < 0.0001***

1.00

0.0004**

  ≥ 30 mm

[1.71–4.23]

2.07

[1.38–3.09]

Lymph node invasion status

 N = 0

0.0386*

1.00

0.0180*

 N ≥ 1

[1.02–2.60]

1.64

[1.09–2.47]

Breast cancer subtypes

 ER + PR ± HER2-

0.0616

N/A

N/A

 ER ± PR ± HER2 + 

[0.62–1.76]

 ER- PR- HER2-

[1.08–3.26]