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Table 1 Association between rRNA 2’-O-Me maturation complex factors and overall survival or disease-free survival using univariate Cox regression analyses in the TTBD series

From: Low level of Fibrillarin, a ribosome biogenesis factor, is a new independent marker of poor outcome in breast cancer

 

Overall survival

Disease-free survival

Variables

HR

CI95%

P-value

HR

CI95%

P-value

FBL (set 1)

 Intermediate

1.00

 

0.0150*

1.00

 

0.0065**

 Low

2.01

[1.25–3.23]

2.06

[1.30–3.27]

 High

1.40

[0.84–2.34]

1.51

[0.93–2.45]

FBL (set 2)

 Intermediate

1.00

 

0.0615

1.00

 

0.0815

 Low

1.69

[1.04–2.75]

1.58

[0.99–2.53]

 High

1.53

[0.92–2.54]

1.52

[0.94–2.46]

NHP2L1

 Intermediate

1.00

 

0.0763

1.00

 

0.0538

 Low

1.67

[1.05–2.66]

1.74

[1.11–2.72]

 High

1.05

[0.63–1.75]

1.20

[0.74–1.93]

NOP56

 Intermediate

1.00

  

1.00

 

0.0604

 Low

1.52

[0.93–2.50]

0.1165

1.46

[0.90–2.36]

 High

1.54

[0.96–2.46]

1.67

[1.07–2.61]

NOP58

 High

1.00

 

0.0031**

1.00

 

0.0078**

 Low

2.01

[1.27–3.20]

1.84

[1.17–2.88]

  1. HR Hazard Ratio, CI95% 95% of Confidence Interval