Fig. 1

Association between FBL mRNA levels and survivals in two independent breast cancer series. Using the cut-offs identified in the Supplementary figure S2 for FBL mRNA expression levels, association between FBL mRNA levels and OS (A, C) and DFS (B, D) was determined using Kaplan–Meier analyses in the TTBD series (n = 216; A-B) and TCGA series (n = 661; C-D). An association between FBL mRNA expression and OS and DFS was observed in the two independent breast cancer series. Patients bearing breast tumors expressing either “low” or “high” FBL mRNA levels exhibited worse survival compared to tumors expressing “int.” FBL mRNA levels. Int.: Intermediate. *: P < 0.05; **:P < 0.01