Questionnaire item | Oesophageal cancer | ||||
---|---|---|---|---|---|
Total n = 107 | Palliative n = 42 (39.3%) | Curative n = 65 (60.7%) | p-value | Absolute difference between means | |
QLQ-C30, mean ± SD | |||||
Global health status1 | 57.5 ± 25.8 | 50.8 ± 28.6 | 62.0 ± 22.9 | 0.030 | 11.2a |
Summary score2 | 74.0 ± 18.7 | 69.0 ± 19.9 | 77.0 ± 17.4 | 0.048 | 8 |
Function’ | |||||
Physical function3 | 76.8 ± 21.0 | 65.5 ± 22.6 | 83.9 ± 16.5 | < 0.001 | 18.4a |
Role function4 | 67.0 ± 35.5 | 55.7 ± 36.6 | 73.9 ± 33.3 | 0.012 | 18.2a |
Emotional function5 | 69.3 ± 24.8 | 68.5 ± 23.5 | 69.8 ± 25.8 | 0.786 | |
Cognitive function6 | 86.5 ± 20.3 | 84.9 ± 20.1 | 87.6 ± 20.5 | 0.505 | |
Social function7 | 74.8 ± 29.5 | 74.2 ± 27.6 | 75.3 ± 30.9 | 0.858 | |
Symptom’’ | |||||
Fatigue8 | 38.3 ± 28.2 | 47.1 ± 27.3 | 32.5 ± 27.5 | 0.010 | 14.6a |
Nausea and vomiting9 | 19.4 ± 25.8 | 24.2 ± 27.2 | 16.4 ± 24.6 | 0.138 | |
Pain10 | 27.6 ± 33.1 | 39.3 ± 37.1 | 19.8 ± 27.8 | 0.005 | 19.5a |
Dyspnoea11 | 28.7 ± 31.4 | 39.5 ± 33.7 | 22.0 ± 28.3 | 0.006 | 17.5a |
Insomnia12 | 36.2 ± 34.8 | 41.3 ± 34.4 | 32.8 ± 34.9 | 0.225 | |
Appetite loss13 | 40.5 ± 41.1 | 48.0 ± 44.1 | 35.5 ± 38.4 | 0.146 | |
Constipation14 | 22.3 ± 31.1 | 20.6 ± 29.4 | 23.5 ± 32.4 | 0.648 | |
Diarrhoea15 | 9.7 ± 17.9 | 12.2 ± 19.4 | 8.1 ± 16.7 | 0.252 | |
Financial difficulties16 | 7.7 ± 18.9 | 7.0 ± 17.6 | 8.2 ± 19.9 | 0.765 | |
QLQ-OG25’’, mean ± SD | |||||
Dysphagia17 | 39.2 ± 31.9 | 42.3 ± 33.3 | 37.0 ± 31.0 | 0.413 | |
Eating restrictions18 | 50.2 ± 35.0 | 54.5 ± 37.7 | 47.3 ± 33.0 | 0.313 | |
Reflux19 | 15.9 ± 25.1 | 21.0 ± 30.4 | 12.3 ± 20.2 | 0.107 | |
Odynophagia20 | 43.3 ± 34.3 | 45.8 ± 38.1 | 41.7 ± 31.8 | 0.555 | |
Pain and discomfort21 | 27.6 ± 36.0 | 30.0 ± 35.2 | 26.0 ± 36.7 | 0.589 | |
Anxiety22 | 64.7 ± 28.7 | 62.3 ± 27.3 | 66.4 ± 29.7 | 0.480 | |
Difficulties eating with others23 | 36.6 ± 41.2 | 38.3 ± 43.1 | 35.5 ± 40.3 | 0.730 | |
Dry mouth24 | 27.3 ± 32.4 | 33.3 ± 33.8 | 23.5 ± 31.2 | 0.142 | |
Sense of taste25 | 17.7 ± 27.8 | 23.3 ± 33.9 | 13.9 ± 22.4 | 0.126 | |
Body image26 | 26.3 ± 33.8 | 36.8 ± 34.0 | 19.4 ± 32.1 | 0.012 | 17.4b |
Saliva27 | 17.5 ± 29.8 | 23.0 ± 34.9 | 13.7 ± 25.4 | 0.141 | |
Choking28 | 26.9 ± 32.2 | 31.0 ± 36.4 | 24.2 ± 29.1 | 0.296 | |
Cough29 | 26.7 ± 28.4 | 31.7 ± 32.9 | 23.3 ± 24.8 | 0.152 | |
Speech30 | 9.6 ± 22.8 | 18.8 ± 31.3 | 3.8 ± 12.2 | 0.006 | 15b |
Weight loss31 | 32.3 ± 36.3 | 33.3 ± 37.7 | 31.7 ± 36.4 | 0.829 | |
Hair loss32 | 15.6 ± 30.5 | 41.7 ± 50.0 | 6.1 ± 13.5 | 0.250 |