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Fig. 2 | BMC Cancer

Fig. 2

From: Baseline soluble MICA levels act as a predictive biomarker for the efficacy of regorafenib treatment in colorectal cancer

Fig. 2

Regorafenib and its metabolites, M2 and M5, inhibited sMICA release in CRC cells. A HCT116 and HT29 cells were treated with regorafenib for 48 h. Cell viabilities (left panels) and sMICA levels (right panels) were determined by the CCK8 assay and ELISA, respectively. B HCT116 and HT29 cells were treated with M2 and M5 for 48 h. Cell viabilities (left panels) and sMICA levels (right panels) were determined by the CCK8 assay and ELISA, respectively. *P < 0.05; **P < 0.005. Error bars represent standard error of the mean. Representative data from three independent experiments with consistently similar results are shown. Reg: regorafenib

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