Table 2 Characteristics of studies reporting overall survival for endometrial cancer patients with diabetes compared to without
Author, year and location | Study Design | Study cohort source/ database | Endometrial cancer study population | Recruitment period | Study size | Diabetes ascertainment | No. of overall deaths | Risk estimate reported | Outcome ascertainment | Follow-up (mean/ median) | NOS score |
|---|---|---|---|---|---|---|---|---|---|---|---|
AlHilli[42] 2016 U.S | Single institution-based | Mayo Clinic | Stage I-IV | 1999–2008 | 516 a | NR | NR | HR | Medical records, tumor registry and death certificates | 4.3 years for DM, 5.2 years for non-DM (median) | 7 |
Bjornsdottir [56] 2020 Sweden | Population-based | Swedish Cancer Registry | NR | 1998–2012 | NR | The Swedish National Diabetes Register | NR | HR | The Total Population Register and Swedish Cause of Death Registry | 6.6 years (median) | 7 |
Chen[62] 2016 Taiwan | Single institution-based | Chang Gung Memorial hospital | Stage I-IV | 2000–2010 | 1450 b | Hospital admissions | 89 | HR | NR | NR | 5 |
Donkers [57] 2021 U.K | Single institution-based | Royal Cornwall Hospital Trust Truro, Cornwall | High grade EC stages I-IV | 2006–2017 | 176 | Medical records | 96 | HR | Medical records | NR | 8 |
Folsom[18] 2004 U.S | Population-based | Iowa women’s health study and SEER cancer registry | Stages I-IV | 1986–2000 | 415 | Self-reported | 93 | RR | Registry, questionnaires and NDI | 6.4 years (median) | 6 |
Gottwald[60] 2011 Poland | Single institution-based | N. Copernicus Memorial Provincial Specialist Hospital | Endometrioid EC stages I-III | 2000–2007 | 260 | NR | 49 | HR | Medical records | NR | 3 |
Hein[45] 2020 Germany | Single institution-based | University of Erlangen | Stages I-IV | 1987–2010 | 287 | Patient files or questionnaire | 113 | HR | Clinical cancer registry | NR | 5 |
Ko[35] 2014 U.S | Multi-institution-based | University of North Carolina hospital and Duke Cancer Institute | Stages I-IV | 2005- 2010 | 1411 | Medical records | NR | HR | NR | NR | 4 |
Kolehmainen [59] 2020 Finland | Single institution-based | Obstetrics and Gynaecology, Helsinki University Hospital | Stages I-IV | 2007–2012 | 515 | Self-reported | 160 | HR | Medical records and death certificates | 6.75 years (median) | 4 |
Kusne [55] 2020 U.S | Single institution-based | Mayo Clinic Hospital | Stages I-IV | 2006–2016 | 96 a | Medical records | 6 | HR | Medical records | 3.9 years (median) | 5 |
Larouzée[29] 2019 France | Population-based | Echantillon Généraliste de Bénéficiaires (EGB) | Stage NR | 2005–2014 | 405 | EGB database | 155 | OR | EGB database | NR | 6 |
Lees [53] 2021 U.S | Population-based | Wisconsin Cancer Registry | Stages I-IV | 2006–2016 | 745 | Structured interview | 450 | HR | National death index | 19.9 years (median) | 8 |
Lemánska[61] 2015 Poland | Single institution-based | Poznan University of Medical Sciences | Stages I-III | 2002–2010 | 107 | Medical database | NR | HR | Greater Poland cancer registry | NR | 5 |
Liang[46] 2016 U.S | Single institution -based | Memorial Sloan Kettering Cancer Centre | High grade stage IA | 1995- 2012 | 85 | NR | 6 | HR | Medical records | 3.9Â years (median) | 5 |
Lindemann[17] 2015 Norway | Population-based | Health surveys of North Trondelag (HUNT) | Stages I-IV | NR | 337 | Self-reported | 166 | HR | Cancer registry | 6.7Â years (median) | 5 |
Linder[43] 2006 Poland | Single institution -based | Maria Sklodowska-Curie Memorial Cancer Centre | Stage I-III | 1992- 1998 | 880 | NR | NR | HR | NR | 8.8Â years (median) | 6 |
Nagle[16] 2018 Australia | Population-based | Australian National EC Study | Stages I-IV | 2005–2007 | 1359 | Self-reported | 179 | HR | Medical records and NDI | 7.1 years (median) | 6 |
Nicholas[52] 2014 U.S | Single institution -based | Tertiary care centre | Stages I-IV | 1992–2008 | 490 | Medical records and self-report | NR | HR | Physician records, hospital cancer registry and obituary surveillance | 4.5 years (median) | 5 |
Olson[21] 2012 U.S | Population-based | SEER-Medicare database | Stages I-IV | 2000- 2005 | 12,568 | Medicare claims | 5,123 | HR | SEER registries | 3.5Â years (median) | 6 |
Ruterbusch[19] 2014 U.S | Single institution-based | Henry Ford Health System (HFHS) tumor registry | Stages I-IV | 1990–2005 | 627 | HFHS, medical records and the MDCSS | 320 | HR | HFHS, medical records and the MDCSS | NR | 6 |
Steiner[63] 2007 Germany and Japan | Multi-institution-based | University hospital and the University of Hokkaido | Stages I-IV | 1985–2003 | 297 | Hospital records | 75 | HR | NR | 3.7 years (mean) | 4 |
Stevens[32] 2012 U.S | Multi-institution-based | Medical centres at the State University of New York and Tumor registry | Endometrioid EC stages I-IV | 2000–2010 | 82 | Medical records and tumor registry | 25 | HR | Tumor registry, medical records and the SSI | NR | 5 |
Strele[36] 2018 Latvia | Population-based cohort | Centre for Disease Prevention and Control of Latvia (cancer registry) | Stages I-IV | 2009–2013 | 1,685 | Diabetes register | 470 | HR | Causes of Death database | 2.5 years for DM and 2.7 years for non-DM (median) | 6 |
Zanders[58] 2013 Netherlands | Population-based | Eindhoven cancer registry | Endometrioid EC stages I-III | 2000- 2008 | 1644 | Medical records | 310 | HR | Municipal personal records | NR | 8 |