Fig. 4
From: OLA1 promotes colorectal cancer tumorigenesis by activation of HIF1α/CA9 axis
mRNA sequencing in OLA1-KO and Ctrl cell lines. Gene expression was analyzed using the Affymetrix Human Genome U133 Plus 2.0 Array. A 113 genes were changed in both pairs of Hct116 and Lovo cell lines. B Functional annotations of differentially expressed genes in OLA1-KO and Ctrl cell lines with functions related to key cellular processes, including regulation of cell proliferation, cell invasion, cell cycle, glucose metabolism and formation of nucleosome structure. C By pathways on gene-set enrichment analysis, Of the 113 common changed genes, 63 genes were hypoxia-related genes.