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Table 1 Demographic and Clinicopathological characteristics (n = 1291)

From: Tumor histology is an independent prognostic factor in locally advanced cervical carcinoma: A retrospective study

 

Squamous-Cell Carcinoma

n(%)

Adenocarcinoma

n(%)

p-value

 

n = 1154 (89.4)

n = 137 (10.6)

 

Age, median (range)

51 (19–87)

47 (26–78)

0.023

BMI median (range)

27 (16.1–56.7)

26.9 (17.5–41.7)

0.73

Performance statusa

  

0.11

 < 80%

166 (14.4)

11 (8.0)

 

90–100%

983 (85.2)

125 (91.2)

Unknown

5 (0.4)

1 (0.7)

FIGO Clinical Stage

  

 < 0.001

IB2

83 (7.2)

24 (17.5)

 

IIA

63 (5.5)

3 (2.2)

IIB

650 (56.3)

94 (68.6)

III

332 (28.8)

14 (10.2)

IVA

26 (2.3)

2 (1.5)

Tumor size, cm

  

0.36

 < 4 cm

348 (30.2)

49 (35.8)

 

 > 4 cm

804 (69.7)

88 (64.2)

Unknown

2 (0.2)

0

Parametrial involvement

  

 < 0.001

Negative

152 (13.2)

27 (19.7)

 

Positive but not up to the pelvic wall

711 (61.6)

96 (70.1)

Extension to the pelvic wall

291 (25.2)

14 (10.2)

Pelvic Lymph-Node Status

  

0.30

Positive

402 (34.8)

43 (31.4)

 

Negative

692 (60.0)

90 (65.7)

Unknown

60 (5.2)

4 (2.9)

Tumor Grade

  

 < 0.001

1 (well differentiated)

9 (0.8)

32 (23.4)

 

2 (moderately differentiated)

861 (74.6)

87 (63.5)

3 (poorly/undifferentiated)

284 (24.6)

18 (13.1)

LVSI b

  

0.002

Yes

130 (11.5)

4 (2.9)

 

No

1024 (88.7)

133 (97.1)

Treatment outcome

  

0.87

Complete response

933 (80.8)

113 (82.5)

 

Partial, progression or stable disease

199 (17.2)

22 (16.1)

Unknown

22 (1.9)

2 (1.5)

Total Recurrence during follow-up

n = 933

n = 113

0.61

 

279 (29.9)

36 (31.9)

  1. a Karnofsky status b lympho-vascular space invasion