Fig. 4
Silencing BIRC5 depressed the tumor growth and survival of PC xenograft mice. Penl1 cells (100 µL containing 1 × 106 cells) in different groups (scrambled shRNA, BIRC5 shRNAb, IFN-γ + scrambled shRNA; IFN-γ + BIRC5 shRNAb) and HacaT cells (control) were subcutaneously inoculated at the right axilla after mice were anesthetized. A Image of tumor growth in living mice. (B, C and D) Tumor volume and tumor weight were measured and survival rate was calculated. The columns were presented as the mean ± SEM. * and ** stands for p < 0.05 and p < 0.01 compared with scrambled shRNA group. ## stands for p < 0.05 compared with IFN-γ + scrambled shRNA group. n = 5 in every group