Table 3 The number of patients experiencing various acute toxicities during chemoradiotherapy (CRT) treatment according to CTCAE (version 5.0) in 93 primary cervical cancer patients
Acute toxicity grade | < 52 years n = 47 (%) | ≥ 52 years n = 46 (%) | p-value |
|---|---|---|---|
Nausea/vomiting | |||
Grade 2 | 15 (31.9) | 14 (30.4) | 0.001 |
Grade ≥ 3 | 3 (6.4) | 24 (52.2) | |
Diarreha | |||
Grade 2 | 24 (51.1) | 25 (54.3) | 0.009 |
Grade ≥ 3 | 3 (6.4) | 17 (37.0) | |
Weight loss | |||
Grade 1 | 10 (21.3) | 17 (37.0) | 0.421 |
Grade ≥ 2 | 0 | 2 (4.3) | |
Limiting ADL | |||
Grade 2 | 2 (4.3) | 1 (2.2) | 0.046 |
Grade ≥ 3 | 1 (2.1) | 16 (34.8) | |
Anemia | |||
Grade 2 | 16 (34.0) | 12 (26.1) | 0.624 |
Grade ≥ 3 | 2 (4.3) | 1 (2.2) | |
Trombocytopenia | |||
Grade 2 | 9 (19.1) | 8 (17.4) | 0.247 |
Grade ≥ 3 | 3 (6.4) | 7 (15.2) | |
Leucopenia | |||
Grade 2 | 12 (25.5) | 9 (19.6) | 0.232 |
Grade ≥ 3 | 9 (19.1) | 14 (30.4) | |
Febrile neutropenia | |||
Grade 2 | 0 | 0 | 1.000 |
Grade ≥ 3 | 5 (10.6) | 11 (23.9) | |
Pain | |||
Grade 2 | 1 (2.1) | 2 (4.3) | 0.333 |
Grade ≥ 3 | 5 (10.6) | 2 (4.3) | |
Urinary symptoms | |||
Grade 2 | 4 (8.5) | 9 (19.6) | 0.571 |
Grade ≥ 3 | 1 (2.1) | 1 (2.2) | |