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Fig. 4 | BMC Cancer

Fig. 4

From: Assessment of the diagnostic and prognostic relevance of ACAT1 and CE levels in plasma, peritoneal fluid and tumor tissue of epithelial ovarian cancer patients - a pilot study

Fig. 4

Ki67 expression in tissue samples. (a) Ki67 mRNA transcript levels assessed via qRT PCR in non-malignant tissue (n = 12, of which 7 had normal ovaries and 5 had benign pelvic masses) and ovarian cancer (EOC, n = 14) tissue samples. Box plots show medians (interquartile ranges) and whiskers (the minimum and maximum values). “d” indicates statistically significant difference compared to EOC (*: p < .05; **: p < .001; ***: p < .0001). (b) Ki67 protein immunostaining in tissue. Ki67 expression shown by DAB staining (brown) in normal human ovary, benign pelvic masses (BMP), low grade EOC and high grade EOC tumor samples. Representative images were taken with an inverted microscope (Olympus H4–100, CCD camera) and a 20X objective. Insets show images photographed with a 40X objective

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