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Table 2 Comparisons of clinicopathological features between cN0 and cN1 of PTC patients

From: Clinicopathological and ultrasound features as risk stratification predictors of clinical and pathological nodal status in papillary thyroid carcinoma: a study of 748 patients

Variable

Total (n = 748)

cN0 (n = 688)

cN1 (n = 60)

χ2

p

Age (years)

   

3.31

0.19

   ≤ 40

246

220 (32.0%)

26 (43.3%)

  

   > 40 and ≤ 55

423

395 (57.4%)

28 (46.7%)

  

   > 55

79

73 (10.6%)

6 (10.0%)

  

Gender

   

1.63

0.20

  Male

108

96 (14.0%)

12 (20.0%)

  

  Female

640

592 (86.0%)

48 (80.0%)

  

HT

   

0.42

0.52

  No

667

612 (89.0%)

55 (91.7%)

  

  Yes

81

76 (11.0%)

5 (8.3%)

  

Nodular goiters

   

2.49

0.12

  No

397

371 (53.9%)

26 (43.3%)

  

  Yes

351

317 (46.1%)

34 (56.7%)

  

Multifocality

   

1.61

0.20

  No

607

562 (81.7%)

45 (75.0%)

  

  Yes

141

126 (18.3%)

15 (25.0%)

  

Bilaterality

   

0.00

0.98

  No

462

425 (61.8%)

37 (61.7%)

  

  Yes

286

263 (38.2%)

23 (38.3%)

  

Primary tumor size

   

74.89

 < 0.001*

   ≤ 1 cm

540

520 (75.6%)

20 (33.3%)

  

   > 1 and ≤ 2 cm

170

145 (21.1%)

25 (41.7%)

  

   > 2 cm

38

23 (3.3%)

15 (25.0%)

  

Capsule contact

   

31.36

 < 0.001*

  No

275

273 (39.7%)

2 (3.3%)

  

  Yes

473

415 (60.3%)

58 (96.7%)

  

ETE

   

82.02

 < 0.001*

  No

505

496 (72.1%)

9 (15.0%)

  

  Yes

243

192 (27.9%)

51 (85.0%)

  

SWE imaging

     

  Emax

748

54.87 ± 14.55

61.70 ± 11.90

-2.92

 < 0.001*

  Emean

748

44.01 ± 11.97

46.80 ± 9.82

-1.36

0.08

  ER

748

1.85 ± 0.46

2.16 ± 0.48

-4.97

 < 0.001*

Central LNM

   

101.56

 < 0.001*

  No

534

525 (76.3%)

9 (15.0%)

  

  Yes

214

163 (23.7%)

51 (85.0%)

  

Number of pN1

   

205.02

 < 0.001*

   ≤ 5 pN1

707

675 (98.1%)

32 (53.3%)

  

   > 5 pN1

41

13 (1.9%)

28 (46.7%)

  
  1. HT Hashimoto's thyroiditis, ETE Extrathyroidal extension, SWE Shear wave elastography, Emax the maximum elasticity values, Emean the mean elasticity values, ER elastic ratio, LNM lymph mode metastasis, pN1 pathologic N1, * statistically significant