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Table 1 Demographic characteristics of patients

From: Diagnostic value of circulating genetically abnormal cells to support computed tomography for benign and malignant pulmonary nodules

Variables

Benign group (n = 34)

Malignancy group (n = 59)

x2 a

P

Gender, n (%)

  

8.654

0.003

  Male

21 (61.8%)

18 (30.5%)

  

  Female

13 (38.2%)

41 (69.5%)

  

Age, year

51.27 ± 10.53

54.17 ± 10.81

1.260b

0.211

Smoking history, n (%)

    

  All patients

  

4.446

0.035

    Yes

10 (29.4%)

7 (11.9%)

  

    No

24 (70.6%)

52 (88.1%)

  

  Male

  

0.300

0.584

    Yes

10 (47.6%)

7 (38.9%)

  

    No

11 (52.4%)

11 (61.1%)

  

  Female

  

-

-

    Yes

0

0

  

    No

13 (100%)

41 (100%)

  

Family history of cancer, n (%)

  

0.431

0.512

  Yes

7 (20.6%)

9 (15.3%)

  

  No

27 (79.4%)

50 (84.7%)

  

Nodule diameter (d), n (%)

  

1.830c

0.419

  5 mm < d ≤ 10 mm

17 (50.0%)

29 (49.2%)

  

  10 mm < d ≤ 20 mm

12 (35.3%)

26 (44.1%)

  

  20 mm < d ≤ 30 mm

5 (14.7%)

4 (6.8%)

  

Type of nodule, n (%)

  

15.267

0.001

  Solid nodule

22 (64.7%)

14 (23.7%)

  

  Mixed ground-glass nodule

5 (14.7%)

19 (32.2%)

  

  Pure ground-glass nodule

7 (20.6%)

26 (44.1%)

  

Solitary nodule, n (%)

  

0.593

0.441

  Yes

10 (29.4%)

22 (37.3%)

  

  No

24 (70.6%)

37 (62.7%)

  

Location of nodule, n (%)

  

0.037

0.848

  Upper lobe

22 (64.7%)

37 (62.7%)

  

  Non-upper lobe

12 (35.3%)

22 (37.3%)

  

Spiculation, n (%)

  

0.555

0.456

  Yes

25 (77.8%)

39 (55.2%)

  

  No

9 (22.2%)

20 (44.8%)

  

Histology, n (%)

  

-

-

  Benign tumour

2 (5.9%)

-

  

  Granuloma

9 (26.5%)

-

  

  Chronic inflammation

18 (52.9%)

-

  

  Otherd

5 (14.7%)

-

  

  Adenocarcinoma

-

57 (96.6%)

  

  Othere

-

2 (3.4%)

  
  1. a The statistic of the Chi-square test
  2. b The statistic of the t-test
  3. c The statistic of Fisher’s exact test
  4. d Including 2 organizing pneumonia, 3 fibrous tissue hyperplasia
  5. e Including 1 squamous cell carcinoma, 1 small cell lung cancer