Table 4 Univariate and multivariate analysis of IRGs signature and clinical characteristics with OS
Gene | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
P value | Hazard ratio | P value | Hazard ratio | |
BMI | 0.037 | 0.693(0.491–0.979) | 0.095 | 0.718(0.412–1.062) |
Age | 0.941 | 0.985(0.670–1.450) |  |  |
Gender | 0.524 | 1.228(0.652–2.312) | 0.088 | 1.790(0.922–3.518) |
Grade | 0.933 | 1.013(0.754–1.360) |  |  |
Stage | 0.014 | 1.452(1.080–1.952) |  |  |
Stage T | 0.008 | 1.493(1.110–2.008) | 0.064 | 1.36(0.98–1.89) |
IRGs risk score | 0.002 | 2.602(1.437–4.709) | 0.022 | 2.15(1.12–4.13) |
Tumor status | 0.081 | 1.652(0.939–2.906) | 0.017 | 2.48(1.18–5.24) |
Family cancer history | 0.671 | 1.130(0.642–1.998) |  |  |
AFP |  < 0.001 | 2.619(1.489–4.607) | 0.012 | 2.24(1.20–4.21) |
Hepatitis B/C | 0.088 | 0.614(0.351–1.075) | 0.035 | 0.73(0.37–1.42) |