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Fig. 8 | BMC Cancer

Fig. 8

From: HOXA-AS2 enhances GBM cell malignancy by suppressing miR-2116-3p thereby upregulating SERPINA3

Fig. 8

miR-2116-3p exerted its function through mediation on SERPINA3 in GBM. A CCK-8 assay was performed to detect cell viability. B EdU assay was used to detect cell proliferation. C The protein levels of Bax, Bcl-2, cleaved-caspase-3, caspase-3 in GBM cells were detected by western blotting. (A-C) U251 and A172 cells were transfected with si-SERPINA3, miR-2116-3p inhibitor, si-SERPINA3 plus miR-2116-3p inhibitor or negative control. *P < 0.05, **P < 0.001 compared with blank group. #P < 0.05, ##P < 0.001 compared with Si-SERPINA3 + inhibitor group. Data were present as mean ± SD

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