Fig. 4
From: HOXA-AS2 enhances GBM cell malignancy by suppressing miR-2116-3p thereby upregulating SERPINA3
HOXA-AS2 sponged miR-2116-3p in GBM. A The potential matching site between HOXA-AS2 and miR-2116-3p was predicted. B Dual-luciferase reporter assay was performed to verify the relationship between HOXA-AS2 and miR-2116-3p. **P < 0.001 compared with miR-2116-3p mimic NC. C HOXA-AS2 could be obviously pulled down by miR-2116-3p mimic showed by RIP analysis. **P < 0.001 compared with anti-IgG. D Lower expression of miR-2116-3p in GBM tissues. **P < 0.001 compared with normal tissues. E Negative correlation between HOXA-AS2 and miR-2116-3p expression. F Lower expression of miR-2116-3p in U251 and A172 cells. **P < 0.001 compared with NHA. G The transfection efficiency of miR-2116-3p inhibitor in U251 and A172 cells by qRT-PCR. *P < 0.05, **P < 0.001 compared with blank group. #P < 0.05, ##P < 0.001 compared with Si-lnc + inhibitor group. Data were present as mean ± SD