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Table 4 Tumour response

From: Safety and efficacy of cabozantinib for patients with advanced hepatocellular carcinoma who advanced to Child–Pugh B liver function at study week 8: a retrospective analysis of the CELESTIAL randomised controlled trial

 

Child–Pugh B subgroup

Overall populationa

 

Cabozantinib (N = 51)

Placebo (N = 22)

Cabozantinib (N = 467)

Placebo (N = 237)

Best overall response, n (%)

    

Complete response

0

0

0

0

Partial response

0

0

18 (4)

1 (< 1)

Stable disease

29 (57)

5 (23)

282 (60)

78 (33)

Progressive disease

21 (41)

15 (68)

98 (21)

131 (55)

Not evaluable or missing

1 (2)

2 (9)

72 (15)

27 (11)

  1. aData from Abou-Alfa et al. N. Engl. J. Med. 379, 54–63 (2018) [11]