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Table 4 Treatment-related adverse events

From: Late combination of transarterial chemoembolization with apatinib and camrelizumab for unresectable hepatocellular carcinoma is superior to early combination

n (%)

TACE plus apatinib plus camrelizumab (n = 80)

All grade

Grade ≥ 3

Hand-foot skin reaction

33 (41.3)

5 (6.3)

Hypertension

35 (43.8)

6 (7.5)

Fatigue

16 (20.0)

2 (2.5)

Mouth ulcers

5 (6.3)

0 (0)

Proteinuria

25 (31.3)

1 (1.3)

Rash

11 (13.8)

0 (0)

Hoarseness

4 (5.0)

0 (0)

Gingival hamorrhage

3 (3.8)

0 (0)

Decreased appetite

14 (17.5)

0 (0)

Diarrhoea

13 (16.3)

2 (2.5)

Hypothyroidism

15 (18.8)

0 (0)

Hyperthyroidism

3 (3.8)

0 (0)

RCCEP

16 (20.0)

0 (0)

Myocarditis

3 (3.8)

1 (1.3)

Haemorrhage, upper GI

3 (3.8)

0 (0)

  1. RCCEP reactive cutaneous capillary endothelial proliferation, GI gastrointestinal tract