Table 1 Characteristics of 63 HER2-positive mCRC
Characteristic | n (%) | n (%) | |
|---|---|---|---|
Age, Years | Tumor Differentiation | ||
< 54 | 30 (47.6) | Poor | 7 (11.1) |
≥ 54 | 33 (52.4) | Medium | 54 (85.7) |
Sex | Well | 2 (3.2) | |
Male | 41 (65.1) | primary lesion resection | |
Female | 22 (34.9) | Yes | 52 (82.5) |
Primary site | No | 11 (17.5) | |
Left semi-colon and rectum | 56 (88.9) | Metastasectomy | |
Right colon | 7 (11.1) | Yes | 19 (30.2) |
Number of metastatic organs | No | 44 (69.8) | |
single/ (liver metastatic) | 22/(18)(34.9) | Status of KRAS NRAS BRAF | |
≥ 2/ (liver metastatic) | 41/(15)(65.1) | Mutant | 9 (14.3) |
Metastatic patterns | WT | 54 (85.7) | |
synchronous | 36 (57.1) | Adjuvant chemotherapy | |
Metachronous | 27 (42.9) | Yes | 25 (39.7) |
Therapy Line | No | 38 (60.3) | |
First-line | 22 (34.9) | local therapies | |
Second-Line | 14 (22.2) | Yes | 23 (36.5) |
Third- or later-line | 27 (42.9) | No | 40 (63.5) |