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Fig. 5 | BMC Cancer

Fig. 5

From: Characterization of SN38-resistant T47D breast cancer cell sublines overexpressing BCRP, MRP1, MRP2, MRP3, and MRP4

Fig. 5

Intracelluar calcein-AM accumulation of the T47D/WT, T47D/SN120 and T47D/SN150 cells. Accumulation of calcein AM decreased in T47D/SN120 and T47D/SN150 cells, compared to that in T47D/WT cells. However, calcein AM accumulation was increased after treatment with MRP inhibitor (probenecid) and ATP deplete cyanide. *, P < 0.05 vs WT (n = 3)

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