Fig. 2From: Characterization of SN38-resistant T47D breast cancer cell sublines overexpressing BCRP, MRP1, MRP2, MRP3, and MRP4Western blot analysis for MRP1, MRP2, MRP3, MRP4 and BCRP protein. MRP1, MRP2, MRP3, and MRP4 expression levels in T47D/SN150 cells were compared with those in T47D/SN120 cells. T47D/SN150 cells overexpressed MRP4 (2.2-fold) and BCRP (4-fold) protein. Compared to T47D/WT cells, which expressed a trace amount of BCRP, T47D/SN120 and T47D/SN150 cells displayed 85.3-fold and 327.5-fold higher BCRP protein expression, respectively. (n = 3)Back to article page