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Fig. 2 | BMC Cancer

Fig. 2

From: Characterization of SN38-resistant T47D breast cancer cell sublines overexpressing BCRP, MRP1, MRP2, MRP3, and MRP4

Fig. 2

Western blot analysis for MRP1, MRP2, MRP3, MRP4 and BCRP protein. MRP1, MRP2, MRP3, and MRP4 expression levels in T47D/SN150 cells were compared with those in T47D/SN120 cells. T47D/SN150 cells overexpressed MRP4 (2.2-fold) and BCRP (4-fold) protein. Compared to T47D/WT cells, which expressed a trace amount of BCRP, T47D/SN120 and T47D/SN150 cells displayed 85.3-fold and 327.5-fold higher BCRP protein expression, respectively. (n = 3)

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