Fig. 3

A Kaplan–Meier curves of overall survival from the beginning of second-line chemotherapy until death or the last follow-up in patients treated with platinum-based chemotherapy and single agent in the second-line setting in the subgroup of patients with an interval of < 8.6 months between the start of first-line CRT and the start of second-line chemotherapy and (B) in the subgroup of patients with an interval of ≥ 8.6 months between the start of first-line CRT and the start of second-line chemotherapy. Tick marks represent data censored at the last time the patient was known to be alive. Abbreviations: CI, confidence interval; CRT, chemoradiotherapy; HR, hazard ratio; OS, overall survival