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Fig. 4 | BMC Cancer

Fig. 4

From: Direct bone marrow injection of human bone marrow-derived stromal cells into mouse femurs results in greater prostate cancer PC-3 cell proliferation, but not specifically proliferation within the injected femurs

Fig. 4

hBMSC-Luc/GFP influence on the frequency of PC-3-DsRed bone lesions. (a) X-ray of mouse legs, or (b) skull of a representative mouse from each group. Red arrows identify lesions. Mice were scored for lesion development with 1, or none with 0. (c) Graphed binary results of total bone lesions occurrence, versus (d) graphed lesions per location. (e) Table of occurrence and frequency of lesions detected at each bone site. All images are found in Supplementary Fig. 11 and 12. Acronyms: I: injected, C: contralateral, L: lateral; PC-3-DsRed n = 7, hBMSC-Luc/GFP + PC-3-DsRed n = 13.

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