Fig. 4
Receiver operator characteristic curves for primary unadjusted A: PRSRLR, B: PRSLRR C: PRSANN, and calibration plots for primary unadjusted D: PRSRLR, E: PRSLRR F: PRSANN. In the calibration plots, each circle represents the predicted OR and observed OR by decile. O/E OR is the ratio of the observed to expected OR, corresponding to the coefficients of the log scale linear regression. OR: odds ratio; PRS: polygenic risk score; RLR: repeated logistic regression; LRR: logistic ridge regression; ANN: Artificial Neural Network; AUC: area under the receiver operator characteristic curve