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Fig. 2 | BMC Cancer

Fig. 2

From: Circ_0058063 contributes to cisplatin-resistance of bladder cancer cells by upregulating B2M through acting as RNA sponges for miR-335-5p

Fig. 2

Knockdown of Circ_0058063 rescued cell viability and induced apoptosis in CDDP-resistant BC cells. A The transfection efficiency of the circ_0058063 downregulation vectors were examined by RT-qPCR. B, C The IC50 value of CDDP in T24/CDDP and 5637/CDDP cells transfected with sh-circ_00058063 or sh-NC was assessed by CCK-8 assay for 48 h. D, E CCK-8 analysis of cell viability of T24/CDDP and 5637/CDDP cells transfected with sh-circ_00058063 or sh-NC. F, G The apoptosis rate of T24/CDDP and 5637/CDDP cells were examined by FCM assay for 48 h. H–K The protein levels of SOX2, OCT4 and NANOG in T24/CDDP and 5637/CDDP cells were detected by Western blot. *P < 0.05

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BMC Cancer

ISSN: 1471-2407

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