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Fig. 8 | BMC Cancer

Fig. 8

From: Prognostic significance of SNCA and its methylation in bladder cancer

Fig. 8

The promoter methylation level of SNCA is upregulated in BLCA and negatively correlates with the expression level of SNCA. A The SNCA promoter methylation level of BLCA patients from TCGA analyzed by UALCAN. The expression level of SNCA methylation in BLCA patients downloaded from UALCAN database was analyzed according to (B) cancer stage, (C) patient’s age, (D) gender, (E) race, and (F) smoking status. G The correlation analysis between the expression level of SNCA and its methylation level in BLCA patients. H qRT-PCR analysis of the expression of SNCA in BLCA cell lines treated with 5-Aza-CdR in a final concentration of 5 μM for 72 h. I Western blotting analysis of the expression of SNCA in BLCA cell lines treated with 5-Aza-CdR in a final concentration of 5 μM for 72 h. GAPDH was used as a loading control. Quantitative analysis results are shown on the right

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