Fig. 3

Co-expression genes of SNCA in BLCA analyzed by LinkedOmics database. A All genes highly correlated with SNCA as identified by Pearson correlation test in the BLCA cohort. B Heat maps showing the top 50 genes positively and negatively correlated with SNCA in BLCA. Red indicates positively correlated genes, and blue indicates negatively correlated genes. C Survival heat maps of the top 50 significant genes positively and negatively correlated with SNCA in BLCA. The survival heat maps show the hazard ratios in the logarithmic scale (log10) for different genes. The red and blue blocks denote higher and lower risks, respectively. The rectangles with frames indicate the significant unfavorable and favorable results in prognostic analyses (p < 0.05). D – E Significantly enriched GO annotations and KEGG pathways of SNCA in the BLCA cohort