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Table 3 Univariate and multivariate Cox analyses of CSS in training set

From: Clinical significance of Osaka prognostic score based on nutritional and inflammatory status in patients with esophageal squamous cell carcinoma

  Univariate analyses Multivariate analyses
HR (95% CI) P value HR (95% CI) P value
Age (years, > 60/≤60) 0.925 (0.687–1.245) 0.606   
Gender (male/female) 0.872 (0.640–1.188) 0.386   
Tumor length (cm, > 3.0/≤3.0) 1.266 (0.919–1.745) 0.149   
Tumor location
 middle/upper 1.175 (0.609–2.266) 0.631   
 lower/upper 1.149 (0.598–2.209) 0.677   
Vessel invasion (yes/no) 1.657 (1.149–2.388) 0.007   
Perineural invasion (yes/no) 1.564 (1.116–2.193) 0.009   
Differentiation
 moderate/well 1.146 (0.745–1.762) 0.534   
 poor/well 1.334 (0.796–2.236) 0.274   
TNM stage
 II/I 1.723 (1.150–2.582) 0.008 1.814 (1.200–2.743) 0.005
 III/I 2.555 (1.734–3.765) < 0.001 1.981 (1.317–2.980) < 0.001
Adjuvant treatment (yes/no) 1.099 (0.796–1.516) 0.567   
PNI (> 47.5/≤47.5) 0.534 (0.398–0.717) < 0.001   
SII (> 588/≤588) 1.816 (1.334–2.471) < 0.001 1.445 (1.046–1.997) 0.026
OPS
 1/0 1.865 (1.272–2.735) 0.001 1.938 (1.310–2.868) 0.001
 2/0 3.043 (1.960–4.725) < 0.001 2.757 (1.762–4.315) < 0.001
 3/0 5.744 (3.090–10.676) < 0.001 4.779 (2.499–9.140) < 0.001
GPS
 1/0 2.092 (1.507–2.906) < 0.001   
 2/0 3.435 (2.158–5.469) < 0.001   
SIS
 1/0 1.637 (1.207–2.221) 0.002   
 2/0 1.914 (1.084–3.379) 0.025   
  1. ESCC Esophageal squamous cell carcinoma, OPS Osaka prognostic score, GPS Glasgow prognostic score, CSS Cancer-specific survival, PNI Prognostic nutritional index, SII Systemic immune-inflammation index, SIS Systemic inflammation score, HR Hazard ratio, CI Confidence interval, TNM Tumor node metastasis