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Table 1 Baseline characteristics of the study population according to the development of laryngeal cancer

From: Synergistic association between underweight and type 2 diabetes on the development of laryngeal cancer: a national population-based retrospective cohort study

Parameter Laryngeal cancer (−) Laryngeal cancer (+) p-value
(n = 9,953,555) (n = 3504)
Age at enrollment, years
 Mean 46.83 ± 14 61.63 ± 9.94 <.0001
Categories, n (%)    <.0001
 20–39 3,196,973 (32.12) 60 (1.71)  
 40–64 5,503,198 (55.29) 2011 (57.39)  
  ≥ 65 1,253,384 (12.59) 1433 (40.9)  
Male, n (%) 5,494,878 (55.2) 3322 (94.8) <.0001
Smoking, n (%)    <.0001
 Nonsmoker 5,889,510 (59.17) 812 (23.17)  
 Ex-smoker 1,422,335 (14.29) 863 (24.63)  
 Current smoker 2,641,710 (26.54) 1829 (52.2)  
Alcohol consumption, n (%)    <.0001
 Nondrinker 5,078,363 (51.02) 1298 (37.04)  
 Mild drinker 4,075,549 (40.95) 1518 (43.32)  
 Heavy drinker 799,643 (8.03) 688 (19.63)  
Regular physical activity, n (%) 1,795,502 (18.0) 782 (22.3) <.0001
Low income (Q1), n (%) 2,133,192 (21.43) 766 (21.86) 0.54
Type 2 diabetes, n (%) 855,037 (8.59) 659 (18.81) <.0001
Anemia, n (%) 1,072,898 (10.78) 422 (12.04) 0.02
Hemoglobin, g/dL 13.97 ± 1.6 14.38 ± 1.42 <.0001
Hypertension, n (%) 2,537,201 (25.49) 1687 (48.14) <.0001
Dyslipidemia, n (%) 1,791,225 (18) 824 (23.52) <.0001
Chronic kidney disease, n (%) 677,243 (6.8) 341 (9.73) <.0001
Height, cm 163.99 ± 9.27 166.01 ± 6.52 <.0001
Weight, kg 64.03 ± 11.67 64.59 ± 10.15 0.01
BMI, kg/m2
 Mean 23.71 ± 3.45 23.38 ± 3.04 <.0001
Categories, n (%)    <.0001
  < 18.5 365,663 (3.67) 155 (4.42)  
 18.5–22.9 3,872,796 (38.91) 1429 (40.78)  
 23–24.9 2,454,246 (24.66) 912 (26.03)  
 25–29.9 2,905,612 (29.19) 932 (26.6)  
  ≥ 30 355,238 (3.57) 76 (2.17)  
Waist circumference, cm 80.24 ± 9.46 83.9 ± 8.14 <.0001
Fasting glucose, mg/dL 97.17 ± 23.8 104.19 ± 28.25 <.0001
Systolic blood pressure, mm Hg 122.4 ± 15.02 128.5 ± 16 <.0001
Diastolic blood pressure, mm Hg 76.3 ± 10.05 78.8 ± 10.08 <.0001
Total cholesterol, mg/dL 195.32 ± 41.39 194.06 ± 49.4 0.07
HDL cholesterol, mg/dL 56.5 ± 32.96 55.96 ± 41.93 0.33
LDL cholesterol, mg/dL 121.35 ± 216.89 111.58 ± 63.37 0.01
  1. Data are mean SD or n (%)
  2. Abbreviations: BMI Body mass index, HDL High-density lipoprotein, LDL Low-density lipoprotein