Parameter | Laryngeal cancer (−) | Laryngeal cancer (+) | p-value |
---|---|---|---|
(n = 9,953,555) | (n = 3504) | ||
Age at enrollment, years | |||
 Mean | 46.83 ± 14 | 61.63 ± 9.94 | <.0001 |
Categories, n (%) | Â | Â | <.0001 |
 20–39 | 3,196,973 (32.12) | 60 (1.71) |  |
 40–64 | 5,503,198 (55.29) | 2011 (57.39) |  |
  ≥ 65 | 1,253,384 (12.59) | 1433 (40.9) |  |
Male, n (%) | 5,494,878 (55.2) | 3322 (94.8) | <.0001 |
Smoking, n (%) | Â | Â | <.0001 |
 Nonsmoker | 5,889,510 (59.17) | 812 (23.17) |  |
 Ex-smoker | 1,422,335 (14.29) | 863 (24.63) |  |
 Current smoker | 2,641,710 (26.54) | 1829 (52.2) |  |
Alcohol consumption, n (%) | Â | Â | <.0001 |
 Nondrinker | 5,078,363 (51.02) | 1298 (37.04) |  |
 Mild drinker | 4,075,549 (40.95) | 1518 (43.32) |  |
 Heavy drinker | 799,643 (8.03) | 688 (19.63) |  |
Regular physical activity, n (%) | 1,795,502 (18.0) | 782 (22.3) | <.0001 |
Low income (Q1), n (%) | 2,133,192 (21.43) | 766 (21.86) | 0.54 |
Type 2 diabetes, n (%) | 855,037 (8.59) | 659 (18.81) | <.0001 |
Anemia, n (%) | 1,072,898 (10.78) | 422 (12.04) | 0.02 |
Hemoglobin, g/dL | 13.97 ± 1.6 | 14.38 ± 1.42 | <.0001 |
Hypertension, n (%) | 2,537,201 (25.49) | 1687 (48.14) | <.0001 |
Dyslipidemia, n (%) | 1,791,225 (18) | 824 (23.52) | <.0001 |
Chronic kidney disease, n (%) | 677,243 (6.8) | 341 (9.73) | <.0001 |
Height, cm | 163.99 ± 9.27 | 166.01 ± 6.52 | <.0001 |
Weight, kg | 64.03 ± 11.67 | 64.59 ± 10.15 | 0.01 |
BMI, kg/m2 | |||
 Mean | 23.71 ± 3.45 | 23.38 ± 3.04 | <.0001 |
Categories, n (%) | Â | Â | <.0001 |
  < 18.5 | 365,663 (3.67) | 155 (4.42) |  |
 18.5–22.9 | 3,872,796 (38.91) | 1429 (40.78) |  |
 23–24.9 | 2,454,246 (24.66) | 912 (26.03) |  |
 25–29.9 | 2,905,612 (29.19) | 932 (26.6) |  |
  ≥ 30 | 355,238 (3.57) | 76 (2.17) |  |
Waist circumference, cm | 80.24 ± 9.46 | 83.9 ± 8.14 | <.0001 |
Fasting glucose, mg/dL | 97.17 ± 23.8 | 104.19 ± 28.25 | <.0001 |
Systolic blood pressure, mm Hg | 122.4 ± 15.02 | 128.5 ± 16 | <.0001 |
Diastolic blood pressure, mm Hg | 76.3 ± 10.05 | 78.8 ± 10.08 | <.0001 |
Total cholesterol, mg/dL | 195.32 ± 41.39 | 194.06 ± 49.4 | 0.07 |
HDL cholesterol, mg/dL | 56.5 ± 32.96 | 55.96 ± 41.93 | 0.33 |
LDL cholesterol, mg/dL | 121.35 ± 216.89 | 111.58 ± 63.37 | 0.01 |