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Table 1 Baseline characteristics of the study population according to the development of laryngeal cancer

From: Synergistic association between underweight and type 2 diabetes on the development of laryngeal cancer: a national population-based retrospective cohort study

Parameter

Laryngeal cancer (−)

Laryngeal cancer (+)

p-value

(n = 9,953,555)

(n = 3504)

Age at enrollment, years

 Mean

46.83 ± 14

61.63 ± 9.94

<.0001

Categories, n (%)

  

<.0001

 20–39

3,196,973 (32.12)

60 (1.71)

 

 40–64

5,503,198 (55.29)

2011 (57.39)

 

  ≥ 65

1,253,384 (12.59)

1433 (40.9)

 

Male, n (%)

5,494,878 (55.2)

3322 (94.8)

<.0001

Smoking, n (%)

  

<.0001

 Nonsmoker

5,889,510 (59.17)

812 (23.17)

 

 Ex-smoker

1,422,335 (14.29)

863 (24.63)

 

 Current smoker

2,641,710 (26.54)

1829 (52.2)

 

Alcohol consumption, n (%)

  

<.0001

 Nondrinker

5,078,363 (51.02)

1298 (37.04)

 

 Mild drinker

4,075,549 (40.95)

1518 (43.32)

 

 Heavy drinker

799,643 (8.03)

688 (19.63)

 

Regular physical activity, n (%)

1,795,502 (18.0)

782 (22.3)

<.0001

Low income (Q1), n (%)

2,133,192 (21.43)

766 (21.86)

0.54

Type 2 diabetes, n (%)

855,037 (8.59)

659 (18.81)

<.0001

Anemia, n (%)

1,072,898 (10.78)

422 (12.04)

0.02

Hemoglobin, g/dL

13.97 ± 1.6

14.38 ± 1.42

<.0001

Hypertension, n (%)

2,537,201 (25.49)

1687 (48.14)

<.0001

Dyslipidemia, n (%)

1,791,225 (18)

824 (23.52)

<.0001

Chronic kidney disease, n (%)

677,243 (6.8)

341 (9.73)

<.0001

Height, cm

163.99 ± 9.27

166.01 ± 6.52

<.0001

Weight, kg

64.03 ± 11.67

64.59 ± 10.15

0.01

BMI, kg/m2

 Mean

23.71 ± 3.45

23.38 ± 3.04

<.0001

Categories, n (%)

  

<.0001

  < 18.5

365,663 (3.67)

155 (4.42)

 

 18.5–22.9

3,872,796 (38.91)

1429 (40.78)

 

 23–24.9

2,454,246 (24.66)

912 (26.03)

 

 25–29.9

2,905,612 (29.19)

932 (26.6)

 

  ≥ 30

355,238 (3.57)

76 (2.17)

 

Waist circumference, cm

80.24 ± 9.46

83.9 ± 8.14

<.0001

Fasting glucose, mg/dL

97.17 ± 23.8

104.19 ± 28.25

<.0001

Systolic blood pressure, mm Hg

122.4 ± 15.02

128.5 ± 16

<.0001

Diastolic blood pressure, mm Hg

76.3 ± 10.05

78.8 ± 10.08

<.0001

Total cholesterol, mg/dL

195.32 ± 41.39

194.06 ± 49.4

0.07

HDL cholesterol, mg/dL

56.5 ± 32.96

55.96 ± 41.93

0.33

LDL cholesterol, mg/dL

121.35 ± 216.89

111.58 ± 63.37

0.01

  1. Data are mean SD or n (%)
  2. Abbreviations: BMI Body mass index, HDL High-density lipoprotein, LDL Low-density lipoprotein