Fig. 3From: Correlation of LAGE3 with unfavorable prognosis and promoting tumor development in HCC via PI3K/AKT/mTOR and Ras/RAF/MAPK pathwaysLAGE3 knockdown suppressed HCC cell proliferation. A The proliferation of SMCC-7721 and Huh-7 cells was significantly inhibited by LAGE3 knockdown in the CCK8 assay, and the data were expressed as the mean ± s. d., ** p < 0.01. B The proliferation of SMCC-7721 and Huh-7 cells was significantly inhibited by LAGE3 knockdown in BrdU assay, and the data were expressed as the mean ± s. d., *** p < 0.001. C The cycle of SMCC-7721 cells was significantly arrested in the S phase by LAGE3 knockdown while the data were expressed as the mean ± s. d., ** p < 0.01, *** p < 0.001. D The cycle of Huh-7 cells was significantly arrested in the G1 phase by LAGE3 knockdown while the data were expressed as the mean ± s. d., *** p < 0.001Back to article page