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Fig. 3 | BMC Cancer

Fig. 3

From: Clinic and genetic similarity assessments of atypical carcinoid, neuroendocrine neoplasm with atypical carcinoid morphology and elevated mitotic count and large cell neuroendocrine carcinoma

Fig. 3

The 425-exon sequencing in 28 pure primary tumour samples revealing 113 altered genes. Abbreviations: X: AC; Y: AC-h; Z: LCNEC; x only: AKT1, PDK1; y only: CREBBP, SMARCA4, NKX2-1, KMT2B, IKBKE, TEK, PIK3R1, RET, SETBP1, EPHA3, PRDM1, TERC, AKT2, TOP2A, CCNE1, CBL, NOTCH2, IDH1, CTCF, AXL; z only: RICTOR, MCL1, ATRX, MYC, ABCB1, FAT1, PALB2, FLT4, TERT, ARID1A, EPHA2, NTRK3, NOTCH1, PDGFRA, BRAF, JAK1, EPHA5, DAXX, ZNF217, ERBB4, TSC2, GATA2, PPARD, SDHC, SDHA, FLCN, TUBB4A, PALLD, SRC, SMAD3, EZH2, BARD1, ATM, AKT3, TPMT, GRIN2A, MAP2K2, BTK, GATA4, MET, RUNX1, BIRC3, CHEK1, DENND1A, PTK2, AXIN2, TGFBR2, PMS2, ARID1B, EP300, POLH, DUSP2, MYCN, IGF1R, DPYD, PREX2, CYSLTR2, CHEK2, EGFR, DDR2, RAD54L, WRN, LZTR1, LHCGR, BRCA1; x–z only overlap: ROS1, MEN1; y–z only overlap: TP53, PTEN, KEAP1, APC, RB1, PKHD1, NTRK1, KIT, PIK3C3, PIK3CA, SOX2, GRM3, LRP1B, GNAS, KRAS, IL7R, POLE, NF1, CRKL, VEGFA, DLL3, CDKN2A, JAK3, STK11

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BMC Cancer

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