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Table 2 Factors associated with 90-day mortality for all patients admitted with colon cancer in 1980–2016; n = 1530

From: Octogenarian patients with colon cancer – postoperative morbidity and mortality are the major challenges

Factors

Unadjusted odds ratio

(95% CI)

P value

Adjusted odds ratio

(95% CI)

P value

Age (years)

  < 65

1 (reference)

 

1 (reference)

 

  65—74

1.44 (0.84 to 2.44)

0.18

1.41 (0.74 to 2.69)

0.30

  75 – 79

1.78 (1.01 to 3.13)

0.045

1.92 (0.95 to 3.88)

0.070

  80—84

3.69 (2.20 to 6.18)

 < 0.001

2.64 (1.35 to 6.16)

0.005

  85 – 89

5.20 (2.91 to 9.30)

 < 0.001

2.42 (1.11 to 5.29)

0.027

  ≥ 90

11.38 (5.70 to 22.72)

 < 0.001

5.85 (2.30 to 14.87)

 < 0.001

Calendar year

0.97 (0.96 to 0.98)

 < 0.001

0.94 (0.92 to 0.96)

 < 0.001

Female sex

0.76 (0.57 to 1.03)

0.072

0.76 (0.52 to 1.13)

0.18

CCI

1.65 (1.39 to 1.95)

 < 0.001

1.39 (1.10 to 1.77)

0.006

ASA score

  1–2

1 (reference)

 

1 (reference)

 

  3

2.82 (1.98 to 4.05)

 < 0.001

1.92 (1.21 to 3.06)

0.006

  4–5

21.59 (13.26 to 35.14)

 < 0.001

6.94 (3.69 to 13.05)

 < 0.001

Anaemiaa

1.44 (1.06 to 1.96)

0.019

1.19 (0.78 to 1.83)

0.42

Emergency surgery

3.12 (2.23 to 4.35)

 < 0.001

4.90 (2.99 to 8.05)

 < 0.001

Localization (left vs. right)

0.87 (0.64 to 1.17)

0.35

0.78 (0.52 to 1.18)

0.24

TNM-stage

  I

1 (reference)

 

1 (reference)

 

  II

2.72 (1.06 to 6.99)

0.038

1.60 (0.54 to 4.74)

0.39

  III

1.17 (0.63 to 4.89)

0.29

1.30 (0.40 to 4.23)

0.67

  IV

17.61 (7.06 to 43.92)

 < 0.001

5.29 (1.57 to 17.80)

0.007

  Unknown

32.71 (11.51 to 92.99)

 < 0.001

1.78 (0.46 to 6.86)

0.40

Treatment intent categories

  Curative intent

    Major resection

1 (reference)

 

1 (reference)

 

    Polypectomy

0.59 (0.08 to 4.43)

0.59

1.59 (0.18 to 13.92)

0.68

  Non-curative intent

    Major resection

5.03 (3.20 to 7.91)

 < 0.001

1.28 (0.55 to 9.98)

0.56

    Bypass/stoma

28.80 (16.22 to 50.83)

 < 0.001

10.23 (4.03 to 26.00)

 < 0.001

  Best supportive care

19.78 (12.95 to 30.21)

 < 0.001

9.56 (4.21 to 21.71)

 < 0.001

  1. Results are from a logistic regression analysis, with death within 90 days as dependent variable; unadjusted: analysis performed with one covariate at a time; adjusted: analysis performed with all listed covariates included simultaneously. CCI Charlson Comorbidity Index, classified in three levels: 0, 1 and 2 + ; aAnaemia was defined as < 13 g/dL in males and < 12 g/dL in women (based on WHO recommendations)
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BMC Cancer

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