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Table 1 Association of circulating lipids with biliary tract cancer risk according to different methods

From: Mendelian randomization study of circulating lipids and biliary tract cancer among East Asians

  HDL LDL CHL TRG
Inverse variance weighted
  OR (95%CI) 1.38 (0.98, 1.94) 1.46 (0.96, 2.23) 1.34 (0.83, 2.16) 0.48 (0.31, 0.74)
  Q statistics (P value) 24.6 (0.431) 20.6 (0.298) 25.5 (0.274) 5.9 (0.662)
MR-egger
  OR (95%CI) 2.10 (0.99, 4.46) 1.36 (0.70, 2.63) 1.50 (0.50, 4.50) 0.46 (0.19, 1.12)
  Q statistics (P value) 23.3 (0.444) 20.5 (0.247) 25.5 (0.228) 5.9 (0.556)
  Intercept (P value) -0.048 (0.274) 0.009 (0.804) -0.009 (0.842) 0.004 (0.946)
Weighted median
  OR (95%CI) 1.55 (0.94, 2.58) 1.74 (1.02, 2.97) 2.16 (1.15, 4.07) 0.46 (0.27, 0.76)
Weighted mode
  OR (95%CI) 1.73 (0.99, 3.02) 1.75 (0.97, 3.14) 2.51 (0.98, 6.40) 0.48 (0.27, 0.83)
  1. HDL high density lipoprotein, LDL low density lipoprotein, CHL cholesterol, TRG triglyceride