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Table 1 Association of circulating lipids with biliary tract cancer risk according to different methods

From: Mendelian randomization study of circulating lipids and biliary tract cancer among East Asians

 

HDL

LDL

CHL

TRG

Inverse variance weighted

  OR (95%CI)

1.38 (0.98, 1.94)

1.46 (0.96, 2.23)

1.34 (0.83, 2.16)

0.48 (0.31, 0.74)

  Q statistics (P value)

24.6 (0.431)

20.6 (0.298)

25.5 (0.274)

5.9 (0.662)

MR-egger

  OR (95%CI)

2.10 (0.99, 4.46)

1.36 (0.70, 2.63)

1.50 (0.50, 4.50)

0.46 (0.19, 1.12)

  Q statistics (P value)

23.3 (0.444)

20.5 (0.247)

25.5 (0.228)

5.9 (0.556)

  Intercept (P value)

-0.048 (0.274)

0.009 (0.804)

-0.009 (0.842)

0.004 (0.946)

Weighted median

  OR (95%CI)

1.55 (0.94, 2.58)

1.74 (1.02, 2.97)

2.16 (1.15, 4.07)

0.46 (0.27, 0.76)

Weighted mode

  OR (95%CI)

1.73 (0.99, 3.02)

1.75 (0.97, 3.14)

2.51 (0.98, 6.40)

0.48 (0.27, 0.83)

  1. HDL high density lipoprotein, LDL low density lipoprotein, CHL cholesterol, TRG triglyceride