Fig. 6From: Innovative mouse models for the tumor suppressor activity of Protocadherin-10 isoformsDevelopment of auricular/pinnal tumors in GFAP-Cretg/+ transgenic mice. A Auricular tumor in a GFAP-Cretg/+;Pcdh10allfl/fl;p53fl/fl;Rbfl/fl mouse at 20 weeks after birth. These pinnal tumors arise only unilaterally in the pinna marked with a monel tag. B Typical histology of a pinnal tumor. Scale bar: 50 μm. C,D Evolution of auricular-tumor free mice with the genotypes indicated. The number of mice evaluated is indicated between brackets. See Additional file 15: Table S11 for statistical analysisBack to article page