Table 1 Descriptive statistics of breast cancer patients with tubule formation Score 2 and 3 are shown for each group and the entire cohort. Values are expressed as mean and standard deviation, apart from Nottingham Prognostic Index (NPI) and proliferative activity marker Ki-67 reported as median and interquartile range. Pathological entries are expressed as number of positive observations
From: Peri-tumoural spatial distribution of lipid composition and tubule formation in breast cancer
Demographic | All (n = 20) | Tubule formation | P-value | |
|---|---|---|---|---|
Score 2 (n = 9) | Score 3 (n = 11) | |||
Age (years) | 57 ± 14 | 62 ± 13 | 54 ± 14 | 0.222 |
Tumour Size (mm) | 26 ± 5 | 27 ± 7 | 26 ± 5 | 0.518 |
Nottingham Prognostic Index (NPI) | 4.44 (3.5 – 4.59) | 3.54 (3.5 – 4.48) | 4.48 (4.42 – 5.16) | 0.094 |
Histological grade | ||||
II | 10 | 7 | 3 | 0.070 |
III | 10 | 2 | 8 | |
Lymph node involvement | 4 | 1 | 3 | 0.591 |
Ki-67 | 12.85 (8.31 – 25.54) | 7.78 (4.96 – 12.68) | 18.56 (12.32 – 32.65) | 0.014* |
Molecular subtypes | ||||
Luminal A | 9 | 6 | 3 | 0.175 |
Luminal B-HER2 negative | 4 | 2 | 2 | 1.000 |
Luminal B-HER2 positive | 4 | 1 | 3 | 0.591 |
Triple Negative | 3 | 0 | 3 | 0.218 |