Fig. 6

The group difference in (a) Mean (n = 9,11) and (b) Skewness (n = 9,11) of SFA are shown in dot plots. Each dot represents a peri-tumoural spatial distribution, and the dots are organised in two columns corresponding to tubule formation Scores. All distributions shown were normally distributed and the error bars indicate the mean and standard deviation. The 2-tailed independent sample t-tests were performed between the groups and p value is shown for each plot. The Spearman’s rank correlation (rho) of (c) Mean (n = 20) and (d) Skewness (n = 20) of SFA against proliferative activity marker Ki-67 are shown in scatter plots. Statistically significant p values (< 0.05) are marked by ‘*’