Fig. 1

Twenty specimens (9/11 for tubule formation Scores 2/3) freshly excised from patients with invasive carcinoma were examined, with proliferative activity marker Ki-67, tumour-infiltrating lymphocytes (TILs) and Nottingham Prognostic Index assessed histologically. Lipid composition maps were acquired using chemical shift-encoded imaging on standard clinical 3 T MRI scanner. The peri-tumoural region was delineated on the first echo of lipid composition images, and adipose voxels within the region were extracted from lipid composition maps to quantify mean, skewness, entropy and kurtosis. Independent sample t-tests and Mann Whitney U tests were conducted between groups, and Spearman’s rank correlation tests performed against prognostic markers