Fig. 2
From: LncRNA CALML3-AS1 suppresses papillary thyroid cancer progression via sponging miR-20a-5p/RBM38 axis
Overexperssion of CALML3-AS1 inhibited cell proliferation, migration and invasion and promoted cell apoptosis. A. CALML3-AS1 was overexpressed in BCPAP and K1 cells by cloning into pcDNA3.1, empty vector was used as a control. B, C. CCK-8 and colony formation assays were used to measure the proliferation ability of BCPAP and K1 cells with EV or CALML3-AS1-OE. D, E. Transwell assays were used to determine the effects of CALML3-AS1 on PTC cell migration and invasion. F. Apoptosis of PTC cells with CALML3-AS1-OE was evaluated with flow cytometry analysis. G. Xenograft model was conducted to study the effect of CALML3-AS1-OE on the tumor growth. *P < 0.05, **P < 0.01