Skip to main content
Fig. 7 | BMC Cancer

Fig. 7

From: Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells

Fig. 7

Effects of knockdown of AGER and AOX1 genes on proliferation of HCC cell lines. Knockdown of AGER and AOX1 genes in Mahlavu and Huh7 cells using 25 nM siRNA validated with q-RT-PCR experiments. Experiments were performed in triplicates and results were represented as means ± SEM. One-Way ANOVA was performed for statistical analysis (A). Cell growth analysis of Mahlavu and Huh7 cells for which siRNA treatments targeting AGER and AOX1 genes were done and cell index values reflecting cell growth were monitored for 72 h. Knockdown of both genes resulted in significant drop in cell proliferation in both cells (B). Experiments were performed in triplicates, and results were represented as means ± SEM. Two-Way ANOVA was performed for statistical analysis. *p < 0.05, **p < 0.01, ***p < 0.001

Back to article page