Table 4 OSNA accuracy compared with histopathological examination in included tumours
Group | Author | H&E positive | H&E negative | Sensitivity | Specificity | Concordance | ||
|---|---|---|---|---|---|---|---|---|
OSNA negative | OSNA positive | OSNA negative | OSNA positive | |||||
1) | Tsujimoto et al. [15] | 0.6 (2) | 13.2 (43) | 85 (276) | 1.2 (4) | 95.6 | 98.6 | 98.2 (319/325) |
Feldman et al. [28] | 3 (31) | 10.2 (107) | 83.1 (868) | 3.6 (38) | 77.5 | 95.8 | 93.4 (975/1044) | |
Le Frère-Belda et al. [29] | 2.4 (12) | 10.1 (51) | 82.1 (413) | 5.4 (27) | 80.9 | 93.9 | 92.2 (464/503) | |
Vegué et al. [30] | 0 (0) | 1.1 (6) | 92.1 (522) | 6.9 (39) | 100 | 93 | 93.1 (528/567) | |
Wang et al. [31] | 2.6 (31) | 13.4 (159) | 78 (927) | 6 (71) | 83.7 | 92.9 | 91.4 (1086/1188) | |
Pathmanathan et al. [32] | 1.8 (3) | 14.7 (25) | 80.6 (137) | 3 (5) | 89.3 | 96.5 | 95.3 (162/170) | |
Banerjee et al. [33] | 0.7 (2) | 14.6 (39) | 81 (217) | 3.7 (10) | 95.1 | 95.6 | 95.5 (256/268) | |
Li et al. [34] | 2 (6) | 9.6 (30) | 85.5 (266) | 2.9 (9) | 83.3 | 96.7 | 95.2 (296/311) | |
2) | Croner et al. [35] | 1.6 (3) | 20.1 (37) | 75.5 (139) | 2.7 (5) | 92.5 | 96.5 | 95.7 (176/184) |
Yamamoto et al. [36] | 1 (4) | 20.5 (79) | 76.6 (295) | 1.8 (7) | 95.2 | 97.7 | 97.1 (374/385) | |
Guller et al. [37] | 0.6 (2) | 16.3 (51) | 79.6 (249) | 3.5 (11) | 96.2 | 95.7 | 95.8 (300/313) | |
Yamamoto et al. [38] | 1 (20) | 6.5 (125) | 89.2 (1717) | 3.3 (63) | 86.2 | 96.5 | 95.7 (1842/1925) | |
Yaguchi et al. [39] | 3.1 (5) | 24.7 (40) | 69.8 (113) | 2.5 (4) | 88.9 | 96.6 | 94.4 (153/162) | |
Kumagai et al. [40] | 2.3 (9) | 11.4 (45) | 82.7 (326) | 3.6 (14) | 83.3 | 95.9 | 94.2 (371/394) | |
Shimada et al. [41] | 1.8 (8) | 3.2 (14) | 93.9 (412) | 1.1 (5) | 63.6 | 98.8 | 97 (426/439) | |
3) | Okamoto et al. [42] | 2.3 (3) | 2.3 (3) | 93.8 (122) | 1.5 (2) | 50 | 98.4 | 96.2 (125/130) |
Nagai et al. [43] | 2.2(3) | 10.2 (14) | 86.9 (119) | 0.7 (1) | 82.4 | 99.2 | 97.1 (133/137) | |
Fanfani et al. [44] | 0.9 (1) | 7.2 (8) | 86.4 (95) | 5.4 (6) | 88.9 | 94.1 | 93.6 (103/110) | |
Kost’un et al. [45] | 0.7 (1) | 7.4 (10) | 78.5 (106) | 13.3 (18) | 90.9 | 85.5 | 85.9 (116/135) | |
4) | Inoue et al. [46] | 0.6 (1) | 11.5 (19) | 87.3 (144) | 0.6 (1) | 95 | 99.3 | 98.8 (163/165) |
Nakagawa et al. [47] | 2.9 (12) | 11.5 (47) | 81.2 (333) | 4.4 (18) | 79.7 | 94.5 | 92.7 (380/410) | |
Escalante-Pérez et al. [48] | 0.1 (1) | 4.8 (34) | 91.3 (644) | 3.7 (26) | 97.1 | 96.1 | 96.2 (678/705) | |
5) | Goda et al. [49] | 2.6 (8) | 17 (53) | 77.2 (241) | 3.2 (10) | 86.9 | 96 | 94.2 (294/312) |
Sofía del Carmen et al. [50] | 5.2 (14) | 28.1 (75) | 60 (160) | 6.7 (18) | 84.2 | 89.9 | 88 (235/267) | |
6) | Engels et al. [24] | 2.2 (12) | 14.2 (76) | 80.5 (452) | 3.4 (18) | 91.4 | 100 | 98.8 (528/534) |