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Table 5 Univariate and multivariate Cox regression analysis for 2-year RFS of HCC patients baseline

From: Development of nomogram models of inflammatory markers based on clinical database to predict prognosis for hepatocellular carcinoma after surgical resection

Variables 2-year recurrence group
(= 112)
Non-recurrence group
(= 248)
Univariate Multivariate
P HR(95% CI) P HR(95% CI)
ALT, U/L (≤50/>50) 89(79.5%)/23(20.5%) 198(79.8%)/50(20.2%) 0.883 0.966(0.611-1.528) 0.002 0.437(0.259-0.740)
ALBI    
-2.6 59(52.7%) 177(71.4%)  
-2.60 - 1.39 51(45.5%) 69(27.8%) <0.001 1.952(1.342-2.841)
>-1.39 2(1.8%) 2(0.8%) 0.127 3.001(0.733-12.292)
AFP,ng/mL       
≤20 34(30.4%) 133(43.6%)  
20-400 26(23.2%) 70(28.2%) 0.130 1.484(0.891-2.474) 0.240 1.361(0.814-2.275)
>400 52(46.4%) 45(18.1%) <0.001 2.987(1.938-4.604) 0.002 2.040(1.305-3.191)
PNI 46.7(26.6,65.8) 49.7(26.5,73.3) 0.001 0.952(0.926-0.979)
APRI 0.27(0.07,4.58) 0.20(0.04,2.16) <0.001 2.006(1.421-2.986) 0.001 2.447(1.460-4.102)
MVI(yes/no) 86(76.8%)/26(23.2%) 94(37.9%)/154(62.1%) <0.001 3.905(2.517-6.060) <0.001 3.027(1.909-4.799)
Number of tumors(solitary/multiple) 80(71.4%)/32(28.6%) 210(84.7%)/38(15.3%) 0.003 1.858(1.233-2.801) 0.039 1.555(1.022-2.365)
Tumor diameter,cm 6.30±3.45 4.39±2.69 <0.001 1.148(1.097-1.202) 0.001 1.095(1.004-1.152)
Tumor capsule(yes/no) 27(24.1%)/85(75.9%) 34(13.7%)/214(86.3%) 0.041 1.570(1.018-2.421)
PVTT(yes/no) 21(18.8%)/91(81.3%) 9(3.6%)/239(96.4%) <0.001 3.666(2.274-5.91) 0.001 2.402(1.453-3.970)