Table 5 Univariate and multivariate Cox regression analysis for 2-year RFS of HCC patients baseline

ALT, U/L (≤50/>50)

89(79.5%)/23(20.5%)

198(79.8%)/50(20.2%)

0.883

0.966(0.611-1.528)

0.002

0.437(0.259-0.740)

ALBI

–

–

–

-2.6

59(52.7%)

177(71.4%)

–

–

–

-2.60 - 1.39

51(45.5%)

69(27.8%)

<0.001

1.952(1.342-2.841)

–

–

>-1.39

2(1.8%)

2(0.8%)

0.127

3.001(0.733-12.292)

–

–

AFP,ng/mL

≤20

34(30.4%)

133(43.6%)

–

–

–

20-400

26(23.2%)

70(28.2%)

0.130

1.484(0.891-2.474)

0.240

1.361(0.814-2.275)

>400

52(46.4%)

45(18.1%)

<0.001

2.987(1.938-4.604)

0.002

2.040(1.305-3.191)

PNI

46.7(26.6,65.8)

49.7(26.5,73.3)

0.001

0.952(0.926-0.979)

–

–

APRI

0.27(0.07,4.58)

0.20(0.04,2.16)

<0.001

2.006(1.421-2.986)

0.001

2.447(1.460-4.102)

MVI(yes/no)

86(76.8%)/26(23.2%)

94(37.9%)/154(62.1%)

<0.001

3.905(2.517-6.060)

<0.001

3.027(1.909-4.799)

80(71.4%)/32(28.6%)

210(84.7%)/38(15.3%)

0.003

1.858(1.233-2.801)

0.039

1.555(1.022-2.365)

Tumor diameter,cm

6.30±3.45

4.39±2.69

<0.001

1.148(1.097-1.202)

0.001

1.095(1.004-1.152)

Tumor capsule(yes/no)

27(24.1%)/85(75.9%)

34(13.7%)/214(86.3%)

0.041

1.570(1.018-2.421)

–

–

PVTT(yes/no)

21(18.8%)/91(81.3%)

9(3.6%)/239(96.4%)

<0.001

3.666(2.274-5.91)

0.001

2.402(1.453-3.970)